Asymmetric synthesis of β-substituted alcanoic acids via highly stereoselective conjugate additions of organocopper compounds to chiral enoates

Lewis acid mediated reactions of organocopper reagents. Entrainment in the conjugate addition to .alpha.,.beta.-unsaturated ketones, esters, and acids via the RCu.cntdot.BF3 system

Yoshinori Yamamoto, Sinichi Yamamoto, Hidetaka Yatagai et al. · The Journal of Organic Chemistry · 1982 · 228 citations

Natural Sciences, Chemistry, Bioorganic Chemistry +8

Camphorsulfonamide‐Shielded, Asymmetric 1,4‐Additions and Enolate Alkylations; Synthesis of a Southern Corn Rootworm Pheromone. Preliminary Communication

Wolfgang Oppolzer, Philip J. Dudfield, Thomas M. Stevenson et al. · Helvetica Chimica Acta · 1985 · 111 citations

Natural Sciences, Chemistry, Bioorganic Chemistry +15

Highly stereoselective addition of organolithium reagents to chiral oxazolines. Asymmetric synthesis of 3-substituted alkanoic acids and 3-substituted lactones

A. I. MEYERS, Richard Smith, Charles E. Whitten · The Journal of Organic Chemistry · 1979 · 111 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

Asymmetric synthesis of β-substituted δ-ketoesters via michael-additions of samp/ramp-hydrazones to α,β-unsaturated esters, virtually complete 1.6-asymmetric induction

Dieter Enders, Kyriakos Papadopoulos · Tetrahedron Letters · 1983 · 73 citations

Natural Sciences, Chemistry, Catalysis +3

A FACILE ASYMMETRIC SYNTHESIS OF β-SUBSTITUTED ALKANOIC ACID THE HIGHLY STEREOSELECTIVE MICHAEL ADDITION OF GRIGNARD REAGENTS TO α,β-UNSATURATED CARBOXYLIC AMIDES DERIVED FROM <scp>l</scp>-EPHEDRINE

Teruaki Mukaiyama, Nobuharu Iwasawa · Chemistry Letters · 1981 · 70 citations

Natural Sciences, Chemistry, Medicinal Chemistry +13