Studies on the Peptide Alkaloids of Discaria febrifuga

Abstract

Abstract A new tryptophan-containing peptide alkaloid, “discarin-K”, has been isolated from Discaria febrifuga, a shrub growing in Brazil, Argentina and Uruguay. Its structure has been determined as 1 on the basis of spectral studies. Another peptide alkaloid, franganin, was also isolated from the same plant and its 1 H NMR and 13 C NMR have been studied using COSY-45, 2 D-J resolved and DEPT techniques.