The hydrofluorocarbon 1,1,1,2-tetrafluoroethane (HFC-134a) as a ready source of trifluorovinyllithium

Abstract

Trifluorovinyllithium has been synthesised in high yield from 1,1,1,2-tetrafluoroethane (HFC 134a) by treatment with butyllithium at –78 °C, and then treated with a variety of electrophiles in one-pot reactions.