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In vitro inhibition, by loratadine and descarboxyethoxyloratadine, of histamine release from human basophils, and of histamine release and intracellular calcium fluxes in rat basophilic leukemia cells (RBL-2H3)

Human BasophilsPharmacological StudyMedicineImmunologyHematologyToxicologyPharmacotherapyExperimental PharmacologyHepatotoxicityPharmacologyHistamine ReleaseIntracellular Calcium FluxesOxidative Stress