FGF-23 Is a Potent Regulator of Vitamin D Metabolism and Phosphate Homeostasis

Abstract

FGF-23 regulates NaPi-2a independently of PTH and the serum 1,25(OH)2D level by controlling renal expressions of key enzymes of the vitamin D metabolism. In conclusion, FGF-23 is a potent regulator of phosphate and vitamin D homeostasis.