Concepedia

Improved Acetylating Radioenzymatic Assay of Amikacin, Tobramycin, and Sisomicin in Serum

Paul Stevens, Lowell S. Young, William L. Hewitt

Antimicrobial Agents and Chemotherapy · 1975 · 31 citations · 6 references

DOIFull text

Open access

Concepts

Abstract

The acetylating radioenzymatic assay of aminoglycosides was modified by using [(3)H]acetyl coenzyme A as cosubstrate. This modification reduces the cost of the method by at least one-half without sacrificing rapidity or accuracy.

References

6

The Release of Enzymes by Osmotic Shock from Escherichia coli in Exponential Phase

Nancy G. Nossal, Leon Heppel · Journal of Biological Chemistry · 1966 · 671 citations · Full text

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Chloramphenicol-, Dihydrostreptomycin-, and Kanamycin-Inactivating Enzymes from Multiple Drug-Resistant Escherichia coli Carrying Episome ‘R’

SUEHIKO OKAMOTO, Yoshiaki Suzuki · Nature · 1965 · 187 citations

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Enzymic acetylation of aminoglycoside antibiotics by Excherichia coli carrying an R factor

Julian Davies, Raoul Ė. Benveniste · Biochemistry · 1971 · 147 citations

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Relation between Dose and Levels of Gentamicin in Blood

Robert E. Winters, Kenneth D. Litwack, William L. Hewitt · The Journal of Infectious Diseases · 1971 · 124 citations

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Enzymatic Acetylation as a Means of Determining Serum Aminoglycoside Concentrations

Michael J. Haas, Julian Davies · Antimicrobial Agents and Chemotherapy · 1973 · 69 citations · Full text

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