Fluid absorption during transurethral resection.

Abstract

During transurethral prostatectomy 1-5% glycine in water is commonly used to irrigate the bladder. Absorption of small quantities of this solution is inconsequential. Occasionally, however, large amounts may be absorbed, leading to severe hyponatraemia. Such severe sodium depletion is associated with electrocardiogram (ECG) changes that include a widened and increased amplitude of QRS complex, T wave inversion,1 and bradycardia. We report on three patients in whom absorption of irrigation fluid during transurethral resection of the prostate led to the death of one and cardiovascular collapse in the other two.