Muscarinic‐mediated vasoconstriction in human, rat and sheep umbilical cords and related vasoconstriction mechanisms

Abstract

Umbilical vessels are significantly different from other vessels in their response to ACh. BKca channels in smooth muscle cells may play important roles in ACh-mediated vasoconstriction in human umbilical cords. This information may be important for fetal medicine and practice with regard to the effect on fetal development of umbilical vascular functions.