Molecular detection and serotypic analysis of enterovirus RNA in archival specimens from patients with acute myocarditis.

Abstract

This study indicates that archival tissue samples, even histologically stained tissue sections, can be used to study the role of enteroviruses in myocardial disease using molecular detection techniques. If a predominant role for coxsackievirus B3 in myocarditis is confirmed by further study, this may have implications for the development of a specific vaccine.