Nitric oxide release triggered by two-photon excited photoluminescence of engineered nanomaterials

Abstract

A new strategy toward controllable release of NO for therapeutic purpose is described. Mn(2+)-doped ZnS quantum dots with NIR-II to visible upconversion properties were encapsulated by chitosan, with which photochemical NO precursors were conjugated to generate nanostructured materials capable of releasing NO under NIR-II irradiation.