Dose‐dependent acute effects of recombinant human TSH (rhTSH) on thyroid size and function: comparison of 0·1, 0·3 and 0·9 mg of rhTSH

Abstract

In healthy individuals, rhTSH-induced thyroid swelling and hyperthyroidism is rapid and dose dependent. If valid for patients with goitre, our results suggest that these adverse effects are unlikely to be of clinical significance, following doses of rhTSH of 0.1 mg or less.