Concepedia

Manganese(ii) complexes of scorpiand-like azamacrocycles as MnSOD mimics

M. Paz Clares, Salvador Blasco, Mario Inclán, Lucas del Castillo Agudo, Begoña Verdejo, Conxa Soriano, Antonio Doménech‐Carbó, Julio Latorre, Enrique García‐España

Chemical Communications · 2011 · 41 citations · 21 references

DOI

Concepts

Abstract

Mn(II) complexes of scorpiand-type azamacrocycles constituted by a tretrazapyridinophane core appended with an ethylamino tail including 2- or 4-quinoline functionalities show very appealing in vitro SOD activity. The observed behaviour is related to structural and electrochemical parameters.

References

21

Superoxide dismutase: Improved assays and an assay applicable to acrylamide gels

Charles Beauchamp, Irwin Fridovich · Analytical Biochemistry · 1971 · 12.8K citations

, , +8

Investigation of equilibria in solution. Determination of equilibrium constants with the HYPERQUAD suite of programs

Paul Gans, Antonio Sabatini, Angelo Vacca · Talanta · 1996 · 3.2K citations

, , +11

Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice.

Russell M. Lebovitz, Henggui Zhang, Hannes Vogel et al. · Proceedings of the National Academy of Sciences · 1996 · 1K citations

, , +17

A Nonpeptidyl Mimic of Superoxide Dismutase with Therapeutic Activity in Rats

Daniela Salvemini, Zhiqiang Wang, Jay L. Zweíer et al. · Science · 1999 · 499 citations

, , +17

Computer-Aided Design (CAD) of Mn(II) Complexes:  Superoxide Dismutase Mimetics with Catalytic Activity Exceeding the Native Enzyme

Karl Aston, Nigam P. Rath, Arati Naik et al. · Inorganic Chemistry · 2001 · 157 citations

, , +17