Optimal regulatory control of bioreactor nutrient concentration incorporating system identification

Studies on on‐line bioreactor identification. I. Theory

Gregory Stephanopoulos, Ka‐Yiu San · Biotechnology and Bioengineering · 1984 · 271 citations

Engineering, Bioengineering, Chemical Engineering +17

Optimal control of the linear regulator with constant disturbances

C.D. Johnson · IEEE Transactions on Automatic Control · 1968 · 258 citations

Natural Sciences, Mathematics, Dynamical Systems +10

Optimal production of secreted protein in fed‐batch reactors

Seujeung Park, W. Fred Ramirez · AIChE Journal · 1988 · 143 citations

Engineering, Bioengineering, Biotechnology +17

Optimal state and parameter identification. An application to batch fermentation

W. Fred Ramirez · Chemical Engineering Science · 1987 · 36 citations

Engineering, Chemical Engineering, Industrial Engineering +14

Adaptive estimation of bioreactors: monitoring plasmid instability

Thomas Chattaway, Gregory Stephanopoulos · Chemical Engineering Science · 1989 · 30 citations

Life Sciences, Bioengineering, Biotechnology +12