Changes in the characteristics of definite Meniere's disease over time in Japan: a long-term survey by the Peripheral Vestibular Disorder Research Committee of Japan, formerly the Meniere's Disease Research Committee of Japan

Abstract

Clear changes were seen over time in the population-adjusted sex distribution of the disease and population-adjusted age at onset. The number of definite MD cases in females increased over time relative to the number of cases in males. The proportion of cases in which onset occurred at 60 years of age or more increased over time when the number of cases in each age group was adjusted for changes in age distribution of the population over time. From the time of the third survey, there was a slight increase in the proportion of cases with bilateral involvement.