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Publication | Open Access

Prelamin A Acts to Accelerate Smooth Muscle Cell Senescence and Is a Novel Biomarker of Human Vascular Aging

DOIFull Paper Access

369

Citations

37

References

2010

Year

Cassandra D. Ragnauth, Derek Warren, Yiwen Liu, Rosamund McNair, Tamara Tajsic, Nichola Figg, Rukshana Shroff, Jeremy N. Skepper, Catherine M. Shanahan
Circulation

Abstract

This study shows that prelamin A is a novel biomarker of VSMC aging and disease that acts to accelerate senescence. It therefore represents a novel target to ameliorate the effects of age-induced vascular dysfunction.

References

YearCitations

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