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The strong inhibition of triosephosphate isomerase by the natural β-carbolines may explain their neurotoxic actions

Molecular PharmacologyMolecular NeuroscienceBiochemistryMedicineTriosephosphate IsomeraseNatural β-CarbolinesMechanism Of ActionNeuropharmacologyExperimental PharmacologyNeuroprotectionPharmacologyNeurochemistryInhibitory ActivityStrong Inhibition