Effect of acute exercise on the raised plasma fibrinogen, soluble P‐Selectin and von willebrand factor levels in chronic atrial fibrillation

Abstract

Patients with chronic AF have increased vWf and fibrinogen levels compared with sinus rhythm. Exercise to exhaustion influences the hypercoagulable state in chronic AF, with a rise in plasma fibrinogen and possible increase in fibrinolytic activity. Nevertheless, acute exercise does not appear to have a significant influence on endothelial dysfunction or platelet activation in patients with AF.