Publication | Closed Access

Toward the development of metal-based synthetic nucleases: DNA binding and oxidative DNA cleavage of a mixed copper(II) complex with N-(9H-purin-6-yl)benzenesulfonamide and 1,10-phenantroline. Antitumor activity in human Caco-2 cells and Jurkat T lymphocytes. Evaluation of p53 and Bcl-2 proteins in the apoptotic mechanism

Medicinal ChemistryDna BindingMixed CopperBiochemistryNatural SciencesMetalloproteinBioactive MetalMetal-based Synthetic NucleasesAnti-cancer AgentRadiation OncologyDrug Discovery