Neocytolysis on Descent from Altitude: A Newly Recognized Mechanism for the Control of Red Cell Mass

Abstract

Neocytolysis and the role of erythropoietin are confirmed in persons with polycythemia who descend from high altitude. This may have implications that extend beyond space and altitude medicine to renal disease and other situations of erythropoietin suppression, hemolysis, and polycythemia.