SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients

Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki et al. · Cell · 2007 · 20.2K citations

Life Sciences, Cell Biology, Developmental Biology +12

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

Stuart M. Chambers, Christopher A. Fasano, Eirini P. Papapetrou et al. · Nature Biotechnology · 2009 · 3.7K citations · Full text

Life Sciences, Molecular Biology, Neurobiology +13

Conserved role of intragenic DNA methylation in regulating alternative promoters

Alika K. Maunakea, Raman P. Nagarajan, Mikhail Bilenky et al. · Nature · 2010 · 1.8K citations

Medicine, Genetics, Molecular Biology +16

Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders

Christelle M. Durand, Catalina Betancur, Tobias M. Boeckers et al. · Nature Genetics · 2006 · 1.6K citations · Full text

Life Sciences, Genetics, Neuroscience +12

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

João Peça, Cátia Feliciano, Jonathan T. Ting et al. · Nature · 2011 · 1.6K citations

Life Sciences, Genetics, Neuroscience +14