Mexiletine antagonizes effects of sotalol on QT interval duration and its proarrhythmic effects in a canine model of torsade de pointes

Torsade de pointes: The long-short initiating sequence and other clinical features: observations in 32 patients

G. Neal Kay, Plumb Vance J., Arciniegas Joaquin G. et al. · Journal of the American College of Cardiology · 1983 · 464 citations

Medicine, Cardiology, Neurology +3

A third class of anti‐arrhythmic action. Effects on atrial and ventricular intracellular potentials, and other pharmacological actions on cardiac muscle, of MJ 1999 and AH 3474

Bramah N. Singh, E. M. Vaughan Williams · British Journal of Pharmacology · 1970 · 382 citations · Full text

Medicine, Cardiology, Pharmacology +17

Electrophysiologic and voltage clamp analysis of the effects of sotalol on isolated cardiac muscle and Purkinje fibers.

Edward Carmeliet · Journal of Pharmacology and Experimental Therapeutics · 1985 · 256 citations

Medicine, Pharmacology, Physiology +17

QTU prolongation and polymorphic ventricular tachyarrhythmias due to bradycardia-dependent early afterdepolarizations. Afterdepolarizations and ventricular arrhythmias.

Nabil El‐Sherif, Robert H. Zeiler, William Craelius et al. · Circulation Research · 1988 · 247 citations

Medicine, Cardiology, Pharmacology +17

Etiology, warning signs and therapy of torsade de pointes. A study of 10 patients.

Andre Keren, Dan Tzivoni, Doron Gavish et al. · Circulation · 1981 · 246 citations · Full text

Medicine, Cardiology, Pharmacology +17