Applied Optics · 1987 · 228 citations · 19 references
EngineeringBiomedical EngineeringBiomedical ImagingBiomedical OpticsFlow VisualizationFlow SensorsHemodynamicsOptical DiagnosticsOptical FlowVascular UltrasonographyBlood FlowBlood Flow MeasurementBlood Flow VisualizationLaser Speckle ImagingLaser-based Flow VisualizationMicrocirculationMicrocirculation VisualizationMicrocirculatory Imaging
A new method is proposed to visualize the microcirculation map using a dynamic laser speckle effect. A skin surface is illuminated by He-Ne laser line spot and its image speckle is detected by a CCD array sensor. The erence between a pair of output data for successive scannings of the image speckles at the sensor plane was calculated and integrated for each pixel. The results were displayed in color graphics showing the spatial variation of the flow level in the area of interest.
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In vivo evaluation of microcirculation by coherent light scattering
Michael D. Stern · Nature · 1975 · 861 citations
Model for laser Doppler measurements of blood flow in tissue
R. F. Bonner, Ralph Nossal · Applied Optics · 1981 · 838 citations