Genetic and immunological factors interact in a mouse model of CNS antiphospholipid syndrome

Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: beta 2-glycoprotein I (apolipoprotein H).

H. Patrick McNeil, Richard J. Simpson, C.N. Chesterman et al. · Proceedings of the National Academy of Sciences · 1990 · 1.6K citations

Pharmacy, Biochemistry, Chromatographic Analysis +15

Induction of primary antiphospholipid syndrome in mice by immunization with a human monoclonal anticardiolipin antibody (H-3).

Ronit Bakimer, Pnina Fishman, Miri Blank et al. · Journal of Clinical Investigation · 1992 · 298 citations · Full text

Life Sciences, Hematology, Immunology +17

Induction of antiphospholipid autoantibodies by immunization with beta 2 glycoprotein I (apolipoprotein H).

A E Gharavi, LR Sammaritano, Jie Wen et al. · Journal of Clinical Investigation · 1992 · 206 citations · Full text

Life Sciences, Immunology, Pathology +15

Antiphospholipid antibodies permeabilize and depolarize brain synaptoneurosomes

Joab Chapman, Malka Cohen‐Armon, Yehuda Shoenfeld et al. · Lupus · 1999 · 194 citations

Life Sciences, Neurology, Neuroscience +12

Immunization with Anticardiolipin Cofactor (Beta-2-Glycoprotein I) Induces Experimental Antiphospholipid Syndrome in Naive Mice

Miri Blank, David Faden, Anǵela Tincani et al. · Journal of Autoimmunity · 1994 · 193 citations

Life Sciences, Immunology, Pathobiology +10