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Comparison of electron and chemical ionization modes by validation of a quantitative gas chromatographic–mass spectrometric assay of new generation antidepressants and their active metabolites in plasma

New Generation AntidepressantsChemical MeasurementGas ChromatographyActive MetabolitesMedicineMass SpectrometryAnalytical ChemistryPharmacotherapyChemical Ionization ModesChemistryMetabolomicsChromatographic AnalysisPharmacologyPharmacokineticsChromatographyDrug Analysis