Non-peptide neuropeptide y antagonists derived from the histamine H2 agonist arpromidine: Role of the guanidine group

Definition and Antagonism of Histamine H2-receptors

J. W. Black, W. A. M. Duncan, C. J. DURANT et al. · Nature · 1972 · 2.3K citations

Medicine, Medicinal Chemistry, Pharmacology +12

The first highly potent and selective non-peptide neuropeptide Y Y1 receptor antagonist: BIBP3226

K Rudolf, Wolfgang Eberlein, Wolfhard Engel et al. · European Journal of Pharmacology · 1994 · 374 citations

Medicine, Neuroscience, Pharmacology +7

Synthesis and in vitro pharmacology of arpromidine and related phenyl(pyridylalkyl)guanidines, a potential new class of positive inotropic drugs

Armin Buschauer · Journal of Medicinal Chemistry · 1989 · 112 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

SR120819A, an orally‐active and selective neuropeptide Y Y1 receptor antagonist

Claudine Serradeil‐Le Gal, Gérard Valette, Pierre-Eric Rouby et al. · FEBS Letters · 1995 · 112 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Neuropeptide Y: a possible role in hypertension?

Martin C. Michel, Wolfgang Rascher · PubMed · 1995 · 88 citations

Medicine, Pharmacology, Physiology +17