Targeting ADAM‐17/notch signaling abrogates the development of systemic sclerosis in a murine model - Concepedia

Concepedia

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Targeting ADAM‐17/notch signaling abrogates the development of systemic sclerosis in a murine model

109

Citations

44

References

2010

Year

Niloufar Kavian, Amélie Servettaz, Céline Mongaret, Andrew Wang, Carole Nicco, Christiane Chéreau, P. Grange, Vincent Vuiblet, Philippe Birembaut, Marie-Danièle Diébold,

Arthritis & Rheumatism

Abstract

Our results show the pivotal role of the ADAM-17/Notch pathway in SSc following activation by reactive oxygen species. The inhibition of this pathway may represent a new treatment of this life-threatening disease.

References

	Year	Citations

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