Concepedia

Digoxin-specific Fab fragments as single first-line therapy in digitalis poisoning

Frédéric Lapostolle, Stephen W. Borron, Carine Verdier, P. Taboulet, Gilles Guerrier, Frédéric Adnet, Jean-Luc Clemessy, C Bismuth, Frédéric J. Baud

Critical Care Medicine · 2008 · 91 citations · 13 references

DOI

Abstract

First-line therapy with Fab fragments in patients with digitalis poisoning was associated with a low mortality rate.

References

13

Treatment of 150 cases of life-threatening digitalis intoxication with digoxin-specific Fab antibody fragments. Final report of a multicenter study.

Elliott M. Antman, T. Wenger, V P Butler et al. · Circulation · 1990 · 392 citations

, , +17

Reversal of Advanced Digoxin Intoxication with Fab Fragments of Digoxin-Specific Antibodies

Thomas W. Smith, Edgar Haber, Lawrence A. Yeatman et al. · New England Journal of Medicine · 1976 · 377 citations

, , +17

Digoxin Immune Fab therapy in the management of digitalis intoxication: Safety and efficacy results of an observational surveillance study

Anne R. Hickey, Thomas L. Wenger, Vincent P. Carpenter et al. · Journal of the American College of Cardiology · 1991 · 188 citations

, , +8

Treatment of 63 severely digitalis-toxic patients with digoxin-specific antibody fragments

Thomas L. Wenger, Vincent P. Butler, Edgar Haber et al. · Journal of the American College of Cardiology · 1985 · 174 citations

, , +5

Hyperkalemia in Acute Digitalis Poisoning: Prognostic Significance and Therapeutic implications

C Bismuth, M Gaultier, F Conso et al. · Clinical toxicology · 1973 · 172 citations

, , +8