On the Behavior of Electrolytes in Gastric Juice Indued by Histamine.

Abstract

Summary. Acidity, chloride, sodium and potassium were determined in gastric juice obtained a t constant rates. The relation of the concentrations of H + , Cl ‐ and Na + to the secretion rate was found to be in accordance with the diffusion theory of TEORELL. The relation between the concentration of potassium and various secretion rates was, however, practically uninfluenced. The total amount of K + was directly proportional to the volume secreted. This was considered to suggest that potassium appears in the gastric juice as a result of the HCI secretory process. This did not contradict a diffusibility of K + through the gastric mucosa.