HEARTBURN IN LATE PREGNANCY. MANOMETRIC STUDIES OF ESOPHAGEAL MOTOR FUNCTION*

Abstract

Heartburn is a burning, often hot sensation which may localize in the throat or substernal region. It is especially common during pregnancy. Gastroesophageal reflux and neuromuscular dys- function of the esophagus have been suggested as underlying pathophysiological mechanisms, but contradictory evidence has prevented a clear definition of the cause of heartburn.