Nuclear Medicine Communications · 1986 · 10 citations · 0 references
MedicineNuclear MedicineRadiologyEndocrine OncologyMetastasisRadionuclide TherapyMedullary Thyroid Carcinoma ImagingRadioiodine TherapyThyroid CancerThyroid ImagingThyroid ScintigraphyThyroid Uptake StudiesCalcitonin-based ImagingIodine-131 Therapy ImagingMedullary Thyroid Carcinoma DiagnosisMetastatic Thyroid Tissue DetectionMetastatic Tumors To The ThyroidPartial ThyroidectomyThyroid Tumor ImagingWhole-body Radioiodine Scan
The uptake of 131I-MIBG by medullary carcinoma of the thyroid was studied in six patients after total thyroidectomy in whom persistent raised plasma calcitonin levels were indicative of residual disease. The only patient in whom any activity in a possible metastasis was seen had by far the highest level of circulating calcitonin of the group and in contrast one patient with a presumptive metastatic deposit showed no uptake of MIBG into it. In conclusion the uptake of 131I-MIBG by medullary carcinoma of the thyroid is unreliable and unpredictable.