Evidence implicating protein kinase C in exocytosis from electropermeabilized bovine chromaffin cells

Inositol trisphosphate, a novel second messenger in cellular signal transduction

Michael J. Berridge, Robin F. Irvine · Nature · 1984 · 6.1K citations

Life Sciences, Biochemistry, Molecular Biology +16

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

Marco Castagna, Yoshimi Takai, Kozo Kaibuchi et al. · Journal of Biological Chemistry · 1982 · 4.8K citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

Hiroyoshi Hidaka, Masaki Inagaki, Sachiyo Kawamoto et al. · Biochemistry · 1984 · 2.7K citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane

Andrew S. Kraft, Wayne B. Anderson · Nature · 1983 · 1.3K citations

Life Sciences, Biochemistry, Cell Biology +12

Role of guanine nucleotide binding protein in the activation of polyphosphoinositide phosphodiesterase

Shamshad Cockcroft, Bastien D. Gomperts · Nature · 1985 · 957 citations

Life Sciences, Biochemistry, Molecular Biology +10