Synthesis of bostrycoidin via directed lithiation of tertiary nicotinamide

Directed lithiation of aromatic tertiary amides: an evolving synthetic methodology for polysubstituted aromatics

Peter Beak, Victor Snieckus · Accounts of Chemical Research · 1982 · 427 citations

Natural Sciences, Chemistry, Medicinal Chemistry +7

The tertiary amide as an effective director of ortho lithiation

Peter Beak, Roger A. Brown · The Journal of Organic Chemistry · 1982 · 201 citations

Natural Sciences, Chemistry, Analytical Chemistry +4

Regiospecific electrophilic substitution of aminopyridines: ortho lithiation of 2-, 3-, and 4-(pivaloylamino)pyridines

James Turner · The Journal of Organic Chemistry · 1983 · 143 citations

Natural Sciences, Chemistry, Medicinal Chemistry +10

Regioselective ortho lithiation of halopyridines

Gordon W. Gribble, Mark G. Saulnier · Tetrahedron Letters · 1980 · 143 citations

Natural Sciences, Chemical Engineering, Chemistry +5

Tandem directed metalation reactions. Short syntheses of polycyclic aromatic hydrocarbons and ellipticine alkaloids

Masahito Watanabe, Victor Snieckus · Journal of the American Chemical Society · 1980 · 101 citations

Natural Sciences, Chemistry, Medicinal Chemistry +10