Concepedia

AgSbF<sub>6</sub>-Promoted Cycloaddition Reaction of 2-Trifluoromethyl-<i>N</i>-tosylaziridine with Aldehydes

Ryoko Maeda, Rie Ishibashi, Ryo Kamaishi, Kensuke Hirotaki, Hiroshi Furuno, Takeshi Hanamoto

Organic Letters · 2011 · 52 citations · 35 references

DOI

Concepts

Abstract

2-Trifluoromethyl-N-tosylaziridine reacted with various aldehydes in the presence of a catalytic amount of AgSbF(6) to provide the corresponding cis-4-trifluoromethyl-2-substituted-N-tosyl-1,3-oxazolidines with excellent regio- and stereoselectivity.

References

35

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Recent developments in regioselective ring opening of aziridines

Pengfei Lu · Tetrahedron · 2010 · 323 citations

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Zinc‐Mediated Formation of Trifluoromethyl Ethers from Alcohols and Hypervalent Iodine Trifluoromethylation Reagents

Raffael Koller, Kyrill Stanek, Daniel Stolz et al. · Angewandte Chemie International Edition · 2009 · 306 citations

, , +2

Cyclocarboamination of Alkynes with Aziridines: Synthesis of 2,3-Dihydropyrroles by a Catalyzed Formal [3 + 2] Cycloaddition

Paul A. Wender, Daniel Strand · Journal of the American Chemical Society · 2009 · 148 citations

, , +11

Silylmethyl-Substituted Aziridine and Azetidine as Masked 1,3- and 1,4-Dipoles for Formal [3 + 2] and [4 + 2] Cycloaddition Reactions

Veejendra K. Yadav, Vardhineedi Sriramurthy · Journal of the American Chemical Society · 2005 · 135 citations

, , +14