Natural Disruption of Group 2 Phospholipase A2 Gene Protects Against Choline-deficient Ethionine-supplemented Diet-induced Acute Pancreatitis and Lung Injury

Abstract

Natural disruption of the group 2 PLA2 gene protects against CDE diet-induced acute pancreatitis and associated lung injury. These findings support the view that group 2 PLA2 is one of the factors in the exacerbation of severe acute pancreatitis.