Libyan Journal of Medicine · 2007 · 27 citations · 158 references
MedicineImmunologyTranslational SciencesRegenerative MedicineStem Cell BiologyStem Cell TransplantationAllogeneic Stem Cell TransplantationCell EngraftmentGraft-versus-host DiseaseMesenchymal Stem Cell TherapyMesenchymal Stromal Cell TherapyBone Marrow Mesenchymal Stem CellsBone Marrow-derived Mesenchymal Stromal CellsMesenchymal Stem Cell EngraftmentMesenchymal Stromal Cell Allogeneic TherapyMesenchymal Stromal Cell Clinical TrialsMesenchymal Stromal Cell EngraftmentSteroid-refractory Graft-versus-host Disease
Mesenchymal stem cells (MSCs) have elicited a great clinical interest, particularly in the areas of regenerative medicine and induction of tolerance in allogeneic transplantation. Previous reports demonstrated the feasibility of transplanting MSCs, which generates new prospects in cellular therapy. Recently, injection of MSCs induced remission of steroid-resistant acute graft-versus-host disease (GVHD). This review summarizes the knowledge and possible future clinical uses of MSCs.
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