Strong negative self regulation of Prokaryotic transcription factors increases the intrinsic noise of protein expression

Stochastic Gene Expression in a Single Cell

Michael B. Elowitz, Arnold J. Levine, Eric D. Siggia et al. · Science · 2002 · 5.6K citations

Engineering, Gene Regulatory Network, Cellular Physiology +17

Intrinsic and extrinsic contributions to stochasticity in gene expression

Peter S. Swain, Michael B. Elowitz, Eric D. Siggia · Proceedings of the National Academy of Sciences · 2002 · 1.7K citations · Full text

Efficient Exact Stochastic Simulation of Chemical Systems with Many Species and Many Channels

Michael Gibson, Jehoshua Bruck · The Journal of Physical Chemistry A · 2000 · 1.7K citations

Engineering, Simulation, Computational Chemistry +18

Regulation of noise in the expression of a single gene

Ertuğrul M. Özbudak, Mukund Thattai, Iren Kurtser et al. · Nature Genetics · 2002 · 1.6K citations · Full text

Transcriptional Regulation, Systems Biology, Genetics +7

Engineering stability in gene networks by autoregulation

Attila Becskei, Luís Serrano · Nature · 2000 · 1.6K citations

Engineering, Gene Networks, Genetics +7