Association of Lower Habitual Physical Activity Level With Mitochondrial and Endothelial Dysfunction in Patients With Stable Coronary Artery Disease

Abstract

In CAD patients, a lower level of habitual PAL is associated with impaired FMD and increased prevalence of mitochondrial dysfunction as defined by high LP ratio. Moreover, high LP ratio predicts a lower FMD, suggesting that the occurrence of mitochondrial dysfunction with lower habitual PAL is associated with endothelial dysfunction in CAD patients.