Electron microscopic observation of crystalline arrays of virus-like particles in tissues of mink with Aleutian disease

Abstract

Aggregates of virus-like particles, which measured about 25 mμ in diameter in the form of crystalline arrays, were observed in the tissues of mink experimentally infected with Aleutian disease (AD). Such structures were not observed in normal control mink. The similarity between these structures and the viral crystals of porcine polioencephalomyelitis and early foot-and-mouth disease virus crystals is emphasized.