Concepedia

Flexible and practical synthesis of 3-oxyindoles through gold-catalyzed intermolecular oxidation of o-ethynylanilines

Chao Shu, Long Li, Xinyu Xiao, Yong‐Fei Yu, Yifan Ping, Jin‐Mei Zhou, Long‐Wu Ye

Chemical Communications · 2014 · 71 citations · 76 references

DOI

Concepts

Abstract

A novel gold-catalyzed intermolecular oxidation of o-ethynylanilines has been developed. A range of functionalized 3-oxyindoles are readily accessed by utilizing this strategy. Importantly, this gold-catalyzed oxidative process outcompetes the typical indole formation.

References

76

A Non-Diazo Approach to α-Oxo Gold Carbenes via Gold-Catalyzed Alkyne Oxidation

Liming Zhang · Accounts of Chemical Research · 2014 · 677 citations · Full text

, , +12

Gold‐Catalyzed Hydroamination of C–C Multiple Bonds

Ross A. Widenhoefer, Xiaoqing Han · European Journal of Organic Chemistry · 2006 · 502 citations

, , +12

Heterocycles from gold catalysis

Matthias Rudolph, A. Stephen K. Hashmi · Chemical Communications · 2011 · 396 citations

, , +13

Catalytic Synthesis of Indoles from Alkynes

Karolin Krüger, Annegret Tillack, Matthias Beller · Advanced Synthesis & Catalysis · 2008 · 388 citations

, , +10

Alkynes as Equivalents of α-Diazo Ketones in Generating α-Oxo Metal Carbenes: A Gold-Catalyzed Expedient Synthesis of Dihydrofuran-3-ones

Long‐Wu Ye, Li Cui, Guozhu Zhang et al. · Journal of the American Chemical Society · 2010 · 376 citations · Full text

, , +16