Journal of the Chemical Society Perkin Transactions 1 · 1979 · 22 citations · 0 references
Life SciencesBiochemistryMarine BiologyMarine EcologySteroid BiochemistryMarine Bioactive CompoundsMarine Natural Product BiosynthesisMarine Natural ProductsSteroid BiosynthesisSteroid Hormone BiochemistrySteroid StructureBioactive Compounds From Marine CoralsBioactive Marine MetabolitesBioactive Marine Natural ProductsMarine Natural Products DiscoveryMarine SterolsMolecular Structure DeterminationSteroid Hormone PrecursorsSterol Structure
The isolation and structure determination of pregna-1,4,20-trien-3-one (1) and a related sterol, pregna-5, 20-dien3β-ol (2) from an Alcyonacean coral, Gersemia rubiformis are described. These compounds were synthesized from appropriate steroid precursors and the orientation of the C-3 hydroxy-function unambiguously established by preparation of the epimer, pregna-5,20-dien-3α-ol.