Concepedia

Butein induces G2/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation

Dong‐Oh Moon, Mun-Ock Kim, Yung Hyun Choi, Jin Won Hyun, Weon Young Chang, Gi‐Young Kim

Cancer Letters · 2009 · 152 citations · 24 references

DOI

Concepts

References

24

Conservation of the Chk1 Checkpoint Pathway in Mammals: Linkage of DNA Damage to Cdk Regulation Through Cdc25

Yolanda Sánchez, Calvin Wong, Richard S. Thoma et al. · Science · 1997 · 1.3K citations

, , +17

cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2

Jean Gautier, Mark J. Solomon, Robert N. Booher et al. · Cell · 1991 · 850 citations

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Ataxia telangiectasia-mutated phosphorylates Chk2 <i>in vivo</i> and <i>in vitro</i>

Shuhei Matsuoka, Galit Rotman, Akira Ogawa et al. · Proceedings of the National Academy of Sciences · 2000 · 823 citations · Full text

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Reactive oxygen species in tumorigenesis.

Daniel I. Feig, Thomas M. Reid, Lawrence A. Loeb · PubMed · 1994 · 476 citations

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Reactive Oxygen Species Generation and Mitochondrial Dysfunction in the Apoptotic Response to Bortezomib, a Novel Proteasome Inhibitor, in Human H460 Non-small Cell Lung Cancer Cells

Yi‐He Ling, Leonard Liebes, Yiyu Zou et al. · Journal of Biological Chemistry · 2003 · 461 citations · Full text

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