HEXOBARBITONE DISPOSITION AT DIFFERENT STAGES OF INTENSIVE CARE TREATMENT

Clearance concepts in pharmacokinetics

Malcolm Rowland, Leslie Z. Benet, Garry G. Graham · Journal of Pharmacokinetics and Biopharmaceutics · 1973 · 761 citations

Therapeutic Drug Monitoring, Pharmacodynamics, Medicine +4

Lidocaine Pharmacokinetics in Advanced Heart Failure, Liver Disease, and Renal Failure in Humans

Pate D. Thomson · Annals of Internal Medicine · 1973 · 511 citations

Heart Failure, Plasma Clearance, Dominant Phase +15

Determination of drug metabolizing enzymes in needle biopsies of human liver

B. Schoene, R. Fleischmann, H. Remmer et al. · European Journal of Clinical Pharmacology · 1972 · 330 citations

Needle Biopsies, Bioanalysis, Drug Test +17

Meperidine kinetics in man; Intravenous injection in surgical patients and volunteers

Laurence E. Mather, Geoffrey T. Tucker, A. Eugene Pflug et al. · Clinical Pharmacology & Therapeutics · 1975 · 200 citations

CLEARANCE AND BIOLOGIC HALF-LIFE AS INDICES OF INTRINSIC HEPATIC METABOLISM

Donald Perrier, Milo Gibaldi · Journal of Pharmacology and Experimental Therapeutics · 1974 · 109 citations