The AMA Journal of Ethic · 2008 · 10 citations · 5 references
MedicineMaternal HealthObstetricsObstetric UltrasoundPrenatal DiagnosisReproductive MedicineAmniotic Fluid AssessmentInvasive Prenatal TestingNoninvasive Prenatal TestingPregnancyPregnancy DiagnosisPrenatal CareAmniocentesis CytogeneticsGestation PeriodNon-invasive Prenatal TestingPrenatal Aneuploidy ScreeningUltrasound GuidanceUltrasound-guided Amniocentesis
Amniocentesis is an invasive procedure that requires removing a sample of amniotic fluid to obtain fetal cells for chromosome analysis. Generally not performed earlier than 15 weeks gestation, the procedure is done under ultrasound guidance. Although some pain is associated with amniocentesis, it is generally well tolerated without the need for anesthesia. Five to 10 percent of pregnant women choose to have the test [1, 2]. Maternal age over 35 is the most common current indication for amniocentesis [3].
5
CHROMOSOME ANALYSIS OF HUMAN AMNIOTIC-FLUID CELLS
MarkW. Steele, W. Roy Breg · The Lancet · 1966 · 450 citations
Screening for Fetal Chromosomal Abnormalities
Obstetrics and Gynecology · 2020 · 381 citations
Revisiting the Fetal Loss Rate After Second-Trimester Genetic Amniocentesis
Anthony Odibo, Diane L. Gray, Jeffrey M. Dicke et al. · Obstetrics and Gynecology · 2008 · 165 citations
K. H. Nicolaides, Frank A. Chervenak, Laurence B. McCullough et al. · American Journal of Obstetrics and Gynecology · 2005 · 122 citations · Full text