Concepedia

Flagellin enhances tumor-specific CD8+ T cell immune responses through TLR5 stimulation in a therapeutic cancer vaccine model

C. Nguyen, Seol Hee Hong, Jeong‐Im Sin, Hong Van Dinh Vu, Kwangjoon Jeong, Kyoung Oh Cho, Satoshi Uematsu, Shizuo Akira, Shee Eun Lee, Joon Haeng Rhee

Vaccine · 2013 · 91 citations · 37 references

DOI

Concepts

References

37

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

Fumitaka Hayashi, Kelly D. Smith, Adrian Ozinsky et al. · Nature · 2001 · 3.6K citations

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Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen.

K Y Lin, Frank Guarnieri, Kevin F. Staveley-O’Carroll et al. · PubMed · 1996 · 1K citations

, , +17

Vaccination with cytotoxic T lymphocyte epitope‐containing peptide protects against a tumor induced by human papillomavirus type 16‐transformed cells

Mariet C.W. Feltkamp, Henk L. Smits, Michel Vierboom et al. · European Journal of Immunology · 1993 · 838 citations

, , +17

Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility

Kelly D. Smith, Erica Andersen‐Nissen, Fumitaka Hayashi et al. · Nature Immunology · 2003 · 813 citations

, , +14

Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5

Satoshi Uematsu, Kosuke Fujimoto, Myoung Ho Jang et al. · Nature Immunology · 2008 · 725 citations

, , +15