Pregnancy and Primary Aldosteronism

Abstract

A case is reported of a 32-yr-old woman with primary aldosteronism in whom metabolic and blood pressure abnormalities were improved during pregnancy. Aldosterone secretion increased throughout pregnancy, as did the acid-labile conjugate of aldosterone-tetrahydroaldosterone ratio, but no complications occurred. After delivery of a normal baby, secretion of aldosterone fell to previously high levels and mild labile hypertension and hypokalemic alkalosis were again present.