A Factorial Approach to Process Variables of Extrusion-Spheronisation of Wet Powder Masses

THE DESIGN OF OPTIMUM MULTIFACTORIAL EXPERIMENTS

R. L. Plackett, J. P. Burman · Biometrika · 1946 · 3.8K citations

Biology, Engineering, Experiment Design +12

Computer Optimization of Pharmaceutical Formulations I: General procedure

Joseph B. Schwartz, Joel R. Flamholz, Robert Press · Journal of Pharmaceutical Sciences · 1973 · 84 citations

Pharmaceutical Formulation, Medicine, Drug Manufacture +5

Optimization of a Slow-Release Tablet Formulation Containing Sodium Sulfathiazole and a Montmorillonite Clay

Michael Harris, J. B. Schwartz, James W. McGinity · Drug Development and Industrial Pharmacy · 1985 · 17 citations

Chemical Engineering, Pharmaceutical Science, Engineering +15

Application of the modern methods of building optimum experimental matrices. II. A study of the Menschutkin reaction

Rosa M. Claramunt, R. Gallo, José Elguero et al. · Journal de Chimie Physique · 1981 · 13 citations

Numerical Analysis, Engineering, Modem Methods +13

An evaluation of the relative importance of formulation and process variables using factorial design

I M Sanderson, J W Kennerley, G D Parr · Journal of Pharmacy and Pharmacology · 1984 · 12 citations