Enhanced invasion of lung adenocarcinoma cells after co-culture with THP-1-derived macrophages via the induction of EMT by IL-6

Cancer statistics, 2012

Rebecca L. Siegel, Deepa Naishadham, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2012 · 10.7K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

Interleukin-6 induces an epithelial–mesenchymal transition phenotype in human breast cancer cells

Nicholas J. Sullivan, A. Kate Sasser, Amy Axel et al. · Oncogene · 2009 · 755 citations

Medicine, Cell Biology, Oncology +16

Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas

Sizhi Paul Gao, Kevin G. Mark, Kenneth Leslie et al. · Journal of Clinical Investigation · 2007 · 664 citations · Full text

Medicine, Cancer Biology, Oncology +17

IL-6 Promotes Head and Neck Tumor Metastasis by Inducing Epithelial–Mesenchymal Transition via the JAK-STAT3-SNAIL Signaling Pathway

Arti Yadav, Bhavna Kumar, Jharna Datta et al. · Molecular Cancer Research · 2011 · 501 citations · Full text

Medicine, Cell Biology, Oncology +17

M2-polarized tumor-associated macrophages promoted epithelial–mesenchymal transition in pancreatic cancer cells, partially through TLR4/IL-10 signaling pathway

Chaoying Liu, Juan-Ying Xu, Xiaoyan Shi et al. · Laboratory Investigation · 2013 · 461 citations · Full text

Life Sciences, Immunology, Oncology +17