Concepedia

RNAi in Human Cells

Ya‐Lin Chiu, Tariq M. Rana

Molecular Cell · 2002 · 395 citations · 28 references

DOIFull text

Open access

Concepts

References

28

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

Andrew Fire, Siqun Xu, Mary K. Montgomery et al. · Nature · 1998 · 15.3K citations · Full text

, , +8

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Sayda M. Elbashir, Jens Harborth, Winfried Lendeckel et al. · Nature · 2001 · 9.4K citations

, , +7

Role for a bidentate ribonuclease in the initiation step of RNA interference

Emily Bernstein, Amy A. Caudy, Scott M. Hammond et al. · Nature · 2001 · 4.9K citations

, , +15

RNA interference is mediated by 21- and 22-nucleotide RNAs

Sayda M. Elbashir, Winfried Lendeckel, Thomas Tuschl · Genes & Development · 2001 · 3.3K citations · Full text

, , +15

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

Scott M. Hammond, Emily Bernstein, David Beach et al. · Nature · 2000 · 3K citations

, , +14