Conversion of 3-oxo steroids into ecdysteroids triggers molting and expression of 20E-inducible genes in Drosophila melanogaster

Shade is the <i>Drosophila</i> P450 enzyme that mediates the hydroxylation of ecdysone to the steroid insect molting hormone 20-hydroxyecdysone

Anna Petryk, James T. Warren, Guillermo Marqués et al. · Proceedings of the National Academy of Sciences · 2003 · 466 citations · Full text

CYP306A1, a Cytochrome P450 Enzyme, Is Essential for Ecdysteroid Biosynthesis in the Prothoracic Glands of Bombyx and Drosophila

Ryusuke Niwa, Takahiro Matsuda, Takuji Yoshiyama et al. · Journal of Biological Chemistry · 2004 · 323 citations · Full text

Genetics, Entomology, Cytochrome P450 Enzyme +17

Spook and Spookier code for stage-specific components of the ecdysone biosynthetic pathway in Diptera

Hajime Ono, Kim Rewitz, Tetsuro Shinoda et al. · Developmental Biology · 2006 · 316 citations

Biology, Spookier Code, Natural Sciences +6

The <i>Drosophila disembodied</i> gene controls late embryonic morphogenesis and codes for a cytochrome P450 enzyme that regulates embryonic ecdysone levels

V. Marcela Chávez, Guillermo Marqués, Jean Paul Delbecque et al. · Development · 2000 · 302 citations

Phantom encodes the 25-hydroxylase of Drosophila melanogaster and Bombyx mori: a P450 enzyme critical in ecdysone biosynthesis

James T. Warren, Anna Petryk, Guillermo Marqués et al. · Insect Biochemistry and Molecular Biology · 2004 · 295 citations

Drosophila Melanogaster, Biosynthesis, Cellular Enzymology +10