To the problem of biologically active conformation of enkephalin

Isolation of an endogenous compound from the brain with pharmacological properties similar to morphine

John Hughes · Brain Research · 1975 · 981 citations

Medicine, Neuroscience, Pharmacology +14

Amino-acids and peptides. XXXIII. Nitrosyl chloride and butyl nitrite as reagents in peptide synthesis by the azide method; Suppression of amide formation

J. Honzl, J. Rudinger · Collection of Czechoslovak Chemical Communications · 1961 · 363 citations

Natural Sciences, Biochemistry, Chemistry +10

Conformation of [Leu⁵]Enkephalin from X-Ray Diffraction: Features Important for Recognition at Opiate Receptor

G. David Smith, Jane F. Griffin · Science · 1978 · 245 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Studies on Arginine Peptides. I. Intermediates in the Synthesis of N-Terminal and C-Terminal Arginine Peptides^*

Leonidas Zervas, Milton Winitz, Jesse P. Greenstein · The Journal of Organic Chemistry · 1957 · 194 citations

Natural Sciences, Chemistry, Biochemical Pharmacology +5

Biosynthetic origin and receptor conformation of methionine enkephalin

A.F. Bradbury, D.G. Smyth, C. R. SNELL · Nature · 1976 · 170 citations

Life Sciences, Biochemistry, Pharmacology +15